Puncturevine

will produce 200 to 5,000 seeds during one growing season. Seeds may remain viable in the soil for up to five years.
infested areas should not be grazed by livestock. The sharp spines of the seed burr can injure the mouth and digestive tract of animals. It is particularly toxic to sheep, causing sensitivity to light resulting in skin lesions and swelling of ears and lips. Severe effects include blindness, necrosis of skin, loss of lips and ears, and death in young animals.

Long-term control can be achieved by reducing the amount of seed in the soil. This is best accomplished by removing plants before they produce seed (i.e., before or at flowering) and continuing to do so over several years. Burrs that have dropped after removing the plant may be collected and removed by sweeping or raking the ground.
Shallow tilling (about 1 inch deep) can be effective in large areas. Hand removal, hoeing, or cultivation should be initiated prior to flowering and seed production. Mowing is not effective since the plant grows low to the ground.
Aeration of compacted sites and planting competitive desirable plants can reduce the impact of this weed by making the area more favorable for the growth of the desired plants.
There are herbicides on the market that, if applied correctly, have proven effective. An early spring treatment of Telar as a pre-emergent application has proven to give season long control. Other products such as those containing 2,4-D or Dicamba have also been used and are best applied after germination to flower stage. Always read and follow the label when using any herbicide.